The Relationship Of Serum Zinc (Zn) Level, Insulin Like Growth Factor-1 (IGF-1), And Hemoglobin (Hb) With Placenta And Anthropometry Of Newborn

Background: Zinc is an essential micromineral as a cofactor of more than 300 metalloenzymes that play an important role in cell regeneration, metabolism, growth, and repair of body tissues. Efforts to prevent fetal growth and development disorders begin in pregnant women, through integrated interventions, including specific nutrition interventions and sensitive nutrition. One of the specific nutritional interventions that can be given to pregnant women besides iron (Fe) is zinc supplementation.
Research purposes: To see the relationship between serum zinc levels, insulin like growth factor-1 (IGF-1) and Hemoglobin to pregnancy outcomes (anthropometry of infants and placenta).
Method: The subject population is normal pregnant women, 20-26 weeks of gestation, height 150 cm, age 19 years, family income below the Regional Minimum Wage of West Sulawesi Province.
Result: The results of statistical tests showed a significant relationship between serum zinc (Zn) levels, pregnant women and infant anthropometry with a significance value of p <0.05, but there was no significant relationship between chest circumference and foot size. Levels of insulin like growth factor-1 (IGF-1) on anthropometry of infants found a significant relationship on body weight, head circumference, chest circumference, abdominal
circumference, with p <0.05
Conclusion: The provision of zinc supplementation for pregnant women is important because it can stimulate the growth and development of the fetus in the womb, especially for adolescent pregnant women who are chronically deficient in energy and of short stature.
Keywords: Zinc, Pregnancy Outcome